Rui Kuang

Rui Kuang

Associate Professor of Computer Science and Engineering
Adjunct Professor of Biomedical Informatics and Computational Biology
Adjunct Professor of Health Informatics

Office: 5-215 Keller Hall
Phone: (612) 624-7820
Fax: (612) 625-0572
Email: kuang at
Address: 4-192 Keller Hall, 200 Union Street SE,
Minneapolis, MN 55455

My broad research interests are in computational biology, biomedical informatics and machine learning. My lab focuses on developing machine-learning algorithms for problems in cancer genomics, biological network analysis and protein function/structure analysis.

Recent Publications

  • Jae-Woong Chang*, Wei Zhang*, Hsin-Sung Yeh, Ebbing de Jong, Semo Jun, Kwan-Hyun Kim, Sun Sik Bae, Kenneth Beckman, Tae Hyun Hwang, Kye-Seong Kim, Do-Hyung Kim, Timothy Griffin, Rui Kuang and Jeongsik Yong, mRNA 3'UTR Shortening is a New mTORC1-activated Molecular Signature Defining the Specificity in Ubiquitin-mediated Proteolysis, Nature Communications, 2015. (*Joint first authors) Accepted.
  • Chien et al, TP53 Mutations, Tetraploidy, and Homologous Recombination Repair Defects in Early Stage High Grade Serous Ovarian Cancer, Nucleic Acids Research, Accepted, 2015
  • MaoQiang Xie, YingJie Xu, YaoGong Zhang, TaeHyun Hwang and Rui Kuang, Network-based Phenome-Genome Association Prediction by Bi-Random Walk, PloS One, 2015. Accepted.
  • Nicholas Johnson, Huanan Zhang, Gang Fang, Vipin Kumar and Rui Kuang, SubPatCNV: approximate subspace pattern mining for mapping copy-number variations, [Paper][Download], BMC Bioinformatics 2015, 16:16.
  • Huanan Zhang, Ze Tian and Rui Kuang , Transfer Learning Across Cancers on DNA Copy Number Variation Analysis, [Paper] Proc. of IEEE International Conference on Data Mining (ICDM), In Press, 2013
  • Jeremy R Chien, Rui Kuang, Charles Landen and Viji Shridhar, Platinum-Sensitive Recurrence in Ovarian Cancer: The Role of Tumor Microenvironment, [Paper], Front Oncol. 2013; 3: 251.
  • Hong Cai, Changjin Hong, Timothy G Lilburn, Armando L Rodriguez, Sheng Chen, Jianying Gu, Rui Kuang and Yufeng Wang, A novel subnetwork alignment approach predicts new components of the cell cycle regulatory apparatus in Plasmodium falciparum, [Paper], BMC Bioinformatics 2013, 14(Suppl 12):S2.
  • Wei Zhang, Takayo Ota, Viji Shridhar, Jeremy R Chien, Baolin Wu and Rui Kuang, Network-based Survival Analysis Reveals Subnetwork Signatures fro Predicting Outcomes of Ovarian Cancer Treatment, [Paper] [Download], PLoS Computational Biology, 9(3):e1002975, 2013
  • Tae Hyun Hwang, Gowtham Atluri, Rui Kuang, Timothy Starr, Kevin AT Silverstein, Peter Haverty, Zemin Zhang, and Jinfeng Liu, Large-scale Integrative Network-based analysis Identifies Common Pathways Disrupted by Copy Number Alterations across Cancers, [Paper] BMC Genomics, 2013 14:440, 2013